Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 5FG5
TargetPeregrin(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50032927(PFI-4 | PFI 4 | PFI4 | N-[2,3-Dihydro-1,3-dimethyl...)
Affinity DataKd:  13nMAssay Description:Binding affinity to BRPF1B (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeregrin(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50032927(PFI-4 | PFI 4 | PFI4 | N-[2,3-Dihydro-1,3-dimethyl...)
Affinity DataIC50: 50nMAssay Description:Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeregrin(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50032927(PFI-4 | PFI 4 | PFI4 | N-[2,3-Dihydro-1,3-dimethyl...)
Affinity DataIC50: 50nMAssay Description:Binding affinity to 6H-Flag-tagged Tev-BRPF1 (622-738 aa) (unknown origin) by TR-FRET competitive assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeregrin(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50032927(PFI-4 | PFI 4 | PFI4 | N-[2,3-Dihydro-1,3-dimethyl...)
Affinity DataIC50: 172nMpH: 7.4 T: 2°CAssay Description:Assays were performed as described previously with minor modifications(Philpott et al., 2011). All reagents were diluted in 25 mM HEPES, 100 mM NaCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)