Report error Found 19 Enz. Inhib. hit(s) for PDB: 5GMH
Affinity DataEC50: 67nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells assessed as activation of NFkappaB incubated for 18 to 24 hrs by SEAP reporter gene based as...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 75nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells incubated for 6 to 16 hrs by SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 250nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as induction of NFkappaB activation by measuring increase in SEAP level by SEAP r...More data for this Ligand-Target Pair
Affinity DataEC50: 260nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 330nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Affinity DataEC50: 420nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Affinity DataEC50: 420nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Affinity DataEC50: 420nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Affinity DataEC50: 420nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Affinity DataEC50: 616nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
Affinity DataEC50: 750nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells assessed as induction of NFKappaB activity after 24 hrs by SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 760nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo...More data for this Ligand-Target Pair
Affinity DataEC50: 1.26E+3nMAssay Description:Agonist activity at TLR7 in human PBMC assessed as induction of IN-12 stimulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.34E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Agonist activity at human TLR7 transfected in HEK cells assessed as NFkappaB induction after 24 hrs by specific secreted alkaline phosphatase gene as...More data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+3nMAssay Description:Activation of TLR7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+3nMAssay Description:Agonist activity at human TLR-7 expressed in HEK293 cells after 24 hrs by SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+3nMAssay Description:Agonist activity at TLR7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+3nMAssay Description:Agonist activity at human TLR7 receptorMore data for this Ligand-Target Pair