Report error Found 7 Enz. Inhib. hit(s) for PDB: 5H15
Affinity DataKi: 600nMAssay Description:Inhibition of OG(488) labeled probe binding to GST-tagged EED (unknown origin) after 1 hr by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 600nMAssay Description:Binding affinity to EED (unknown origin) by TR-FRET based binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Binding affinity to GST tagged EED (unknown origin) after 1 hr by OG(488) probe based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nM ΔG°: -33.8kJ/molepH: 7.5 T: 2°CAssay Description:For the assay, compounds were dispensed in assay-ready plates using a three-fold serial dilution from 50 μM to ~850 pM using an Echo 550 Acousti...More data for this Ligand-Target Pair
Affinity DataIC50: 1.57E+3nMAssay Description:Binding affinity to his tagged EED (1 to 441 residues) (unknown origin) incubated for 20 mins in presence of biotinylated H3K27me3 peptide (19 to 33 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.57E+3nMAssay Description:Binding affinity to his tagged EED (1 to 441 residues) (unknown origin) incubated for 20 mins in presence of biotinylated H3K27me3 peptide (19 to 33 ...More data for this Ligand-Target Pair
Affinity DataKd: 3.80E+4nMAssay Description:Binding affinity to biotin labelled human EED (78 to 441 residues) by SPR assayMore data for this Ligand-Target Pair