Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) for PDB: 5IGN
TargetBromodomain-containing protein 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50157607(CHEMBL3753082 | US11773085, Compound B24)
Affinity DataKd:  99nMAssay Description:Binding affinity to recombinant human BRD9 by isothermal calorimetric titration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50157607(CHEMBL3753082 | US11773085, Compound B24)
Affinity DataKd:  100nMAssay Description:Binding affinity to BRD9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50157607(CHEMBL3753082 | US11773085, Compound B24)
Affinity DataKd:  99nMAssay Description:Binding affinity to human partial length BRD9 (R130 to V259 residues) by bromoKdELECT Discover assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50157607(CHEMBL3753082 | US11773085, Compound B24)
Affinity DataKd:  99nMAssay Description:Inhibition of BRD9 (unknown origin) by Isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50157607(CHEMBL3753082 | US11773085, Compound B24)
Affinity DataKd:  99nMAssay Description:Binding affinity to BRD9 (unknown origin) by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50157607(CHEMBL3753082 | US11773085, Compound B24)
Affinity DataKd:  99nMAssay Description:Inhibition of human BRD9 isoform 1 by VP-ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50157607(CHEMBL3753082 | US11773085, Compound B24)
Affinity DataKd:  99nMAssay Description:Binding affinity to human BRD9 by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 9 [133-239](Human)
Foghorn Therapeutics

US Patent
LigandPNGBDBM50157607(CHEMBL3753082 | US11773085, Compound B24)
Affinity DataIC50: 550nMAssay Description:A mixture of biotinylated-ligand and SureLight Allophycocyanin-Streptavidin (APC-SA, PerkinElmer AD0201) in 50 mM HEPES (pH 7.4), 50 mM NaCl, 1 mM TC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetBromodomain-containing protein 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50157607(CHEMBL3753082 | US11773085, Compound B24)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human BRD9 isoform 1 co-expressed with H3 histone family 3A in HEK293 cells preincubated for 18 hrs followed by addition of nano-BRET f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50157607(CHEMBL3753082 | US11773085, Compound B24)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human BRD9 isoform 1 co-expressed with H4 histone in HEK293 cells preincubated for 18 hrs followed by addition of nano-BRET furimazine ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)