Report error Found 11 Enz. Inhib. hit(s) for PDB: 5IKQ
Affinity DataIC50: 40nMAssay Description:Inhibition of the human Prostaglandin G/H synthase 2 was determined by thin-layer chromatography assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for its inhibitory activity against CO(cyclooxygenase)More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Compound was evaluated in an intact RBL-1 cell line for inhibition of 5-CyclooxygenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of the murine wild type Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of the murine Arg120Ala mutant type COX-2More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair

3D Structure (crystal)