Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) for PDB: 5JKG
TargetFibroblast growth factor receptor 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50189781(CHEMBL3828009)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant FGFR4 (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50189781(CHEMBL3828009)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant non-phosphorylated FGFR4 kinase domain (442 to 753) (unknown origin) expressed in Sf9 insect cells using 5-Fluo-Ahx-KKKKEEI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50189781(CHEMBL3828009)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of wild type FGFR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50189781(CHEMBL3828009)
Affinity DataIC50: 6nMAssay Description:Inhibition of FGFR4 (unknown origin) incubated for 30 mins by trilux reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50189781(CHEMBL3828009)
Affinity DataIC50: 6nMAssay Description:Inhibition of FGFR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50189781(CHEMBL3828009)
Affinity DataIC50: 6nMAssay Description:Inhibition of FGFR4 (unknown origin) using poly[Glu:Tyr] (4:1) substrate and ATP and [gamma33P]-ATP incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 4(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50189781(CHEMBL3828009)
Affinity DataIC50: 10nMAssay Description:Inhibition of FGFR4 in mouse BAF3 cells assessed as decrease in FGFR4 phosphorylation incubated for 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50189781(CHEMBL3828009)
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal 6His-tagged FGFR4 (unknown orgin) (445 to 753 residues) expressed in Rosetta (NEB) cells using Tyr 04 peptide as substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 4(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50189781(CHEMBL3828009)
Affinity DataIC50: 76nMAssay Description:Inhibition of FGFR4 in mouse BAF3 cells assessed as reduction in cell viability incubated for 2 days by cell proliferation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)