Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 5JQ7
TargetEnvelope glycoprotein(ZEBOV)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM58492(2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]...)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to Ebola virus Zaire Mayinga-76 recombinant GP protein by SYPRO orange dye-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEnvelope glycoprotein(ZEBOV)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM58492(2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]...)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to EBOV Mayinga, Zaire, 1976 envelope glycoprotein extracellular domain T42A mutant tagged with 6xHis/foldon trimerization sequence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEnvelope glycoprotein(ZEBOV)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM58492(2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]...)
Affinity DataEC50:  63nMAssay Description:Inhibition of HIV/EBOV GP Y517S mutant infected in 293T cells assessed as reduction in virus entryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEnvelope glycoprotein(ZEBOV)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM58492(2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]...)
Affinity DataEC50:  63nMAssay Description:Inhibition of HIV/EBOV GP T519V mutant infected in 293T cells assessed as reduction in virus entryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)