Report error Found 5 Enz. Inhib. hit(s) for PDB: 5K0I
Affinity DataIC50: 2nMAssay Description:Inhibition of human mPGES-1 expressed in 293E cells assessed as reduction in conversion of PGH2 to PGE2 after 1.5 min by LC/MS analysisMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 5nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in recombinant human interleukin-1 beta-induced PGE2 production preincubated for 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of mPGES-1 in human whole blood assessed as reduction in LPS-induced PGE2 production preincubated for 30 mins followed by LPS stimulation ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of dog mPGES-1More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of mPGES-1 in dog whole bloodMore data for this Ligand-Target Pair