Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 5KNJ
TargetMixed lineage kinase domain-like protein(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM5832(3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...)
Affinity DataKd:  530nMAssay Description:Binding affinity to full length human MLKL pseudokinase domain by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMixed lineage kinase domain-like protein(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM5832(3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...)
Affinity DataKd:  530nMAssay Description:Binding affinity to full length MLKL (unknown origin) expressed in human HEK293 cells assessed as dissociation constant incubated for 30 mins by Comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMixed lineage kinase domain-like protein(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM5832(3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...)
Affinity DataKd:  530nMAssay Description:Binding affinity to full length human MLKL assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMixed lineage kinase domain-like protein(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM5832(3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...)
Affinity DataKd:  9.30E+3nMAssay Description:Binding affinity to MLKL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)