Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 5KR9
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23451(5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.0^{2,7}....)
Affinity DataIC50: 11nMAssay Description:Binding affinity against human estrogen receptor alpha in competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23451(5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.0^{2,7}....)
Affinity DataIC50: 75.7nMAssay Description:Binding affinity for human Estrogen receptor AlphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23451(5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.0^{2,7}....)
Affinity DataIC50: 75.7nMAssay Description:The binding affinity and selectivity of candidate molecules yielded from database screening were determined by a fluorescent polarization competitive...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23451(5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.0^{2,7}....)
Affinity DataIC50: 75.7nMAssay Description:Binding affinity for human Estrogen receptor AlphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)