Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 5KTW
TargetCREB-binding protein(Human)
Genentech

US Patent
LigandPNGBDBM50200431(CHEMBL3889679 | US9763922, Example 218)
Affinity DataIC50: 20nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
LigandPNGBDBM50200431(CHEMBL3889679 | US9763922, Example 218)
Affinity DataIC50: 30nMAssay Description:Displacement of biotinylated ligand from recombinant His-tagged CBP/EP300 (unknown origin) measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50200431(CHEMBL3889679 | US9763922, Example 218)
Affinity DataIC50: 960nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to CBP/EP300 (unknown origin) expressed in HEK293 cells measured after overnight incubation by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)