Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 5KUP
TargetTyrosine-protein kinase BTK(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50594231(CHEMBL5195945)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of His-tagged full-length recombinant wild-type human BTK (Ala2 to Ser659 residues) expressed in baculovirus infected insect cells incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50594231(CHEMBL5195945)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of BTK C481S mutant (unknown origin) expressed in baculovirus infected Sf9 insect cells incubated for 30 mins in presence of ATP by Microf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50594231(CHEMBL5195945)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of BTK C481R mutant (unknown origin) expressed in baculovirus infected Trichoplusia ni pro cells incubated for 30 mins in presence of ATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50594231(CHEMBL5195945)
Affinity DataIC50: 43nMAssay Description:Inhibition of BTK T474M mutant (unknown origin) expressed in baculovirus infected Trichoplusia ni pro cells incubated for 30 mins in presence of ATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50594231(CHEMBL5195945)
Affinity DataIC50: 439nMAssay Description:Inhibition of BTK T474I mutant (unknown origin) expressed in baculovirus infected Trichoplusia ni pro cells incubated for 30 mins in presence of ATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)