Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) for PDB: 5L3E
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50507295(CHEMBL1232432)
Affinity DataKd:  243nMAssay Description:Binding affinity to LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetREST corepressor 1(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50507295(CHEMBL1232432)
Affinity DataKd:  243nMAssay Description:Binding affinity to LSD1/CoREST (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetREST corepressor 1(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50507295(CHEMBL1232432)
Affinity DataKd:  243nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetREST corepressor 1(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50507295(CHEMBL1232432)
Affinity DataKd:  243nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3K4me peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50507295(CHEMBL1232432)
Affinity DataKd:  243nMAssay Description:Binding affinity to LSD1 (unknown origin) assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetREST corepressor 1(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50507295(CHEMBL1232432)
Affinity DataKd:  2.43E+5nMAssay Description:Inhibition of human LSD1-CoREST expressed in Escherichia coli assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50507295(CHEMBL1232432)
Affinity DataKd:  243nMAssay Description:Binding affinity to LSD1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50507295(CHEMBL1232432)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human LSD1 (unknown orgin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetREST corepressor 1(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50507295(CHEMBL1232432)
Affinity DataKi:  440nMAssay Description:Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetREST corepressor 1(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50507295(CHEMBL1232432)
Affinity DataKi:  440nMAssay Description:Inhibition of human LSD1-CoREST expressed in Escherichia coli assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50507295(CHEMBL1232432)
Affinity DataKi:  440nMAssay Description:Binding affinity to LSD1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)