Report error Found 2 Enz. Inhib. hit(s) for PDB: 5LGT
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology
Curated by ChEMBL
European Institute of Oncology
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
3D Structure (crystal)TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology
Curated by ChEMBL
European Institute of Oncology
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:Competitive inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using H3K4me peptide as substrate preincubated for 15 ...More data for this Ligand-Target Pair