Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 5LXD
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of DYRK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50: 323nMAssay Description:Inhibition of recombinant human DYRK2 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of DYRK2 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)