Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 5LYJ
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bovine)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 900nMAssay Description:Inhibition of bovine brain tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bovine)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization assessed as protein assembly after 20 mins by turbidimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bovine)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization extent after 20 mins by turbidimetricallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bovine)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bovine)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)