Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 5M0M
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501623(CHEMBL4062929)
Affinity DataIC50: 20nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Rat)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50501623(CHEMBL4062929)
Affinity DataIC50: 20nMAssay Description:Inhibition of rat ATX lysoPLD activity using LPC as substrate assessed as reduction in choline release measured after 60 mins by HVA fluorescence bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501623(CHEMBL4062929)
Affinity DataKi:  6nMAssay Description:Competitive inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in LPC hydrolysis measured every 30 secs for 90 mins by Lin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)