Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 5N93
TargetDual specificity protein kinase TTK(Human)
Jilin University

Curated by ChEMBL
LigandPNGBDBM50420401(CHEMBL2089255 | US11208696, Example 31)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of MPS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase TTK(Human)
Jilin University

Curated by ChEMBL
LigandPNGBDBM50420401(CHEMBL2089255 | US11208696, Example 31)
Affinity DataIC50: 7nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetDual specificity protein kinase TTK(Human)
Jilin University

Curated by ChEMBL
LigandPNGBDBM50420401(CHEMBL2089255 | US11208696, Example 31)
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal 6XHis-tagged/GST-tagged full length human MPS1 expressed in recombinant baculovirus infected sf9 insect cells using 5FAM-DHT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase TTK(Human)
Jilin University

Curated by ChEMBL
LigandPNGBDBM50420401(CHEMBL2089255 | US11208696, Example 31)
Affinity DataIC50: 560nMAssay Description:Inhibition of Myc-tagged wild type MPS1 autophosphorylation in human HCT116 cells after 2 hrs in presence of proteosome inhibitor MG132More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)