Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 5NBA
TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM170763(US9085555, 191)
Affinity DataIC50: 48nMpH: 7.5 T: 2°CAssay Description:Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compound at vario...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM170763(US9085555, 191)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human complement factor D catalytic domain using Z-Lys-thiobenzylester as substrate preincubated for 1 hr followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)