Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 5OFW
TargetD-3-phosphoglycerate dehydrogenase(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50232874(CHEMBL4074617)
Affinity DataKd:  1.50E+6nMAssay Description:Binding affinity to human PHGDH ( 1 to 533 residues) expressed in Escherichia coli Rosetta (DE3) by Sypro-orange dye based differential scanning fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD-3-phosphoglycerate dehydrogenase(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50232874(CHEMBL4074617)
Affinity DataKd:  1.60E+6nMAssay Description:Binding affinity to human PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetD-3-phosphoglycerate dehydrogenase(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50232874(CHEMBL4074617)
Affinity DataKd:  1.60E+6nMAssay Description:Binding affinity to human N-terminal His6-tagged truncated PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)