Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 5OP8
TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM118339(US8653111, 72)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of recombinant human FIH using 2OG as substrate and Fe2 as co-factor assessed as hydroxylation incubated for 15 mins in presence of L-asco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM118339(US8653111, 72)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of FIH (unknown origin) by solid-phase extraction coupled to MS based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)