Report error Found 7 Enz. Inhib. hit(s) for PDB: 5T1A
Affinity DataIC50: 0.240nMAssay Description:Antagonist activity against CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis at 37 degCMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMT: 2°CAssay Description:Inhibition of [125I]hMCP1 binding to CCR2 in human PBMC incubated for 30 mins at room temperatureMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Antagonist activity against CCR2 in whole blood (unknown origin) assessed as reduction in CD11b upregulationMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]-CCR2-RA-[R] from wild type human CCR2 expressed in CHO cell membranes incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]-CCR2-RA-[R] from wild type human CCR2 expressed in CHO cell membranes incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Negative allosteric modulation of CCR2 (unknown origin)More data for this Ligand-Target Pair