Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 5T1U
TargetBeta-secretase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50259973(CHEMBL4098403)
Affinity DataIC50: 18nMAssay Description:Inhibition of BACE1 in human H4 cells expressing wild type APP695 assessed as reduction in soluble APPbeta level after 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50259973(CHEMBL4098403)
Affinity DataIC50: 69nMAssay Description:Inhibition of BACE1 (unknown origin) using biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH as substrate after 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)