Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 5T2D
LigandPNGBDBM50234158(CHEMBL4072500)
Affinity DataIC50: 0.794nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50234158(CHEMBL4072500)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50234158(CHEMBL4072500)
Affinity DataIC50: 90nMAssay Description:Inhibition of PI3Kdelta-mediated AKT phosphorylation at ser473 residue in human JeKo1 cells preincubated for 60 mins followed by anti-IgM stimulation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)