Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 5TT7
TargetTyrosine-protein kinase SYK(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM50204294(CHEMBL3943295 | US20230295171, Example 8)
Affinity DataIC50: 7.94nMAssay Description:YK protein is prepared from cDNA encoding human spleen tyrosine kinase and is expressed in insect cells using a baculovirus expression vector. The cD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase SYK(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM50204294(CHEMBL3943295 | US20230295171, Example 8)
Affinity DataIC50: 7.94nMAssay Description:YK protein is prepared from cDNA encoding human spleen tyrosine kinase and is expressed in insect cells using a baculovirus expression vector. The cD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase SYK(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM50204294(CHEMBL3943295 | US20230295171, Example 8)
Affinity DataIC50: 13nMAssay Description:Inhibition of human C-terminal 6His-tagged SYK (356 to 635 residues) expressed in Sf9 insect cells using 5-carboxyfluorescein(FAM)-EEPLYWSFPAKKK-NH2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase SYK(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM50204294(CHEMBL3943295 | US20230295171, Example 8)
Affinity DataEC50:  35nMAssay Description:Inhibition of SYK in TgM-stimulated human Ramos cells expressing RA1/GFP-tagged BLNK assessed as reduction in RA1/GFP-tagged BLNK phosphorylation pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)