Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 5UPG
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
The State University of New York

US Patent
LigandPNGBDBM50485076(CHEMBL2023402 | US20250099433, Compound 1-(R))
Affinity DataKi:  0.0150nMAssay Description:A fluorescence-based competition assay was used to determine the kinetic parameters for binding of the inhibitors to paLpxC. This assay is based on t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50485076(CHEMBL2023402 | US20250099433, Compound 1-(R))
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Pseudomonas aeruginosa LpxC expressed in Escherichia coli using UDP-3-O-N-acetylglucosamine substrate measured after 30 mins by mass sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)