Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 5VZS
TargetBromodomain-containing protein 4(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataKd:  4.60nMAssay Description:Binding affinity to BRD4 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: 5.10E+3nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged BRD4 bromodomain-1 measured after 10 mins by TR-FRET assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50269847(CHEMBL4097025)
Affinity DataIC50: 1.20E+4nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged BRD4 bromodomain-2 measured after 10 mins by TR-FRET assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)