Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 5WBO
TargetKetohexokinase(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241206(CHEMBL1500542)
Affinity DataKd:  6.20E+4nMAssay Description:Binding affinity to recombinant His-tagged human KHK expressed in Escherichia coli in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKetohexokinase(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241206(CHEMBL1500542)
Affinity DataKd:  6.20E+4nMAssay Description:Binding affinity to full length recombinant human biotin-labeled KHK by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKetohexokinase(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241206(CHEMBL1500542)
Affinity DataIC50: 3.16E+5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKetohexokinase(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241206(CHEMBL1500542)
Affinity DataIC50: 3.19E+5nMAssay Description:Inhibition of recombinant His-tagged human KHK expressed in Escherichia coli in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKetohexokinase(Human)
Terns Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241206(CHEMBL1500542)
Affinity DataIC50: 3.19E+5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)