Affinity DataEC50: 8nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated f...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 13nMAssay Description:Inhibition of IFNgamma-stimulated IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 8.70nMAssay Description:Inhibition of human IDO1 expressed in HEK293 cells assessed as reduction in kynurenine production after 30 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 5.08E+4nMAssay Description:Inhibition of IDO1 in human HCT-116 cells using L-Tryptophan as substrate incubated for 24 hrs by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 80nMAssay Description:Inhibition of IDO1 in IFN-gamma induced overexpressing human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKd: 3.46E+3nMAssay Description:Binding affinity to NT650-NHS fluorophore-labeled recombinant human N-terminal His-tagged IDO1 expressed in Escherichia coli measured after 10 mins b...More data for this Ligand-Target Pair
Affinity DataEC50: 5.39E+4nMAssay Description:Inhibition of IDO1 in human HeLa cells using L-Tryptophan as substrate incubated for 24 hrs by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human OCI-AML2 cells assessed as reduction in kynurenine productionMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of recombinant human His-tagged IDO1 (Ala2 to Gly403 residues) expressed in Escherichia coli using tryptophan as substrate preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells using L-tryptophan as substrate measured after 48 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibition of IDO1 in IFN-gamma/LPS stimulated human THP-1 cells assessed as reduction in kynurenine production after 24 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine production incubated for 18 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Inhibition of IFN-gamma stimulated IDO1 in human HeLa cells assessed as reduction in formation of kynurenine incubated for 48 hrs in presence of IFNg...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Inhibition of IDO1 in recombinant human IFNgamma and LPS-induced human HeLa assessed as reduction in kynurenine production incubated for 2 days by sp...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Inhibition of IFN-gamma-stimulated IDO1 activity in human HeLa cells using L-tryptophan as substrate after 48 hrs by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Inhibition of IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of IDO1 in interferon-gamma-induced human SKOV3 cells assessed as N-formylkynurenine formation using L-tryptophan as substrate measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 9.60nMAssay Description:Inhibition of human IDO1 expressed in HEK293T cells assessed as reduction in N-formylkynurenine production incubated for 12 hrs by microplate reader ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine production incubated for 24 hrs relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant IDO1 assessed as reduction in kynurenine production using L-tryptophan incubated for 60 mins by Ehrlich's reagent bas...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of IDO1 in human HeLa cells using L-tryptophan as substrate incubated for 48 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human IDO1 using L-tryptophan as substrate assessed as reduction in N-formyl kynurenine formation by UV-visible spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of IDO1 in IFNgamma and LPS-stimulated human dendritic cells co-cultured with human T cells assessed as inhibition of T-cell proliferation...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of IDO1 in human HeLa cells assessed as production of N-formylkynurenine using tryptophan as substrate in presence of inactivated fetal bo...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells using L-tryptophan as substrate incubated for 48 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human IDO1 expressed in HEK293 cells assessed as N-formylkynurenine formation by measuring kynurenine level incubated for 1...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human IDO1 expressed in HEK293/MSR cells assessed as reduction in kynurenine production incubated fro 2 daysMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant IDO1 in human HeLa cells assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate preinc...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells using tryptophan as substrate measured after 48 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of IDO1 in IFN-gamma treated human HeLa cells incubated for 48 hrs by absorbance based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in kynurenine formation using L-tryptophan as substrate by absorbanc...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of IDO1 in IFN-gamma-induced human HeLa cells assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate preinc...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human THP1 cells assessed as reduction in kynurenine productio by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of human IDO1 expressed in Escherichia coli Rosetta using tryptophan as substrate incubated for 1 hr by methylene blue based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli EC538 assessed as reduction in N-formylkynurenine formation using L-tryptophan as ...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in kynurenine formation measured after 48 hrs by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli EC538 assessed as reduction in N-formylkynurenine formation using L-tryptophan as ...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli BL21 cells using L-tryptophan as substrate incubated for 30 mins by methylene blue...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of human N-terminal His-tagged IDO1 expressed in Escherichia coli assessed as formation of N'-formyl-kynurenine using D-tryptophan as a su...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli BL21 (DE3) using tryptophan as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant IDO1 measured after 60 mins by fluorescence based analysisMore data for this Ligand-Target Pair
