Report error Found 4 Enz. Inhib. hit(s) for PDB: 5WO4
Affinity DataIC50: 0.100nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 0.120nMAssay Description:The basic assay protocol is as follows: First, 250 nL of diluted compounds in DMSO were dispensed into the wells of a dry 384-well Black plate (Grein...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of JAK1 in IL6-stimulated human ME180 cells expressing stably integrated beta-lactamase reporter gene under control of sis-inducible eleme...More data for this Ligand-Target Pair
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of JAK1 in human whole blood assessed as decrease in cytokine-stimulated STAT phosphorylation preincubated for 20 mins followed by cytokin...More data for this Ligand-Target Pair