Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 5WYX
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50587872(CHEMBL4553089)
Affinity DataIC50: 67nMAssay Description:Inhibition of human TLR8More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50587872(CHEMBL4553089)
Affinity DataIC50: 67nMAssay Description:Antagonist activity at human TLR8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50587872(CHEMBL4553089)
Affinity DataIC50: 67nMAssay Description:Antagonist activity at R848 stimulated TRL8 overexpressed in HEK293 cells measured after 20 to 24 hrs by SEAP reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50587872(CHEMBL4553089)
Affinity DataKd:  220nMAssay Description:Binding affinity to human TLR8 expressed in HEK-Blue hTLR8 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)