Report error Found 5 Enz. Inhib. hit(s) for PDB: 5WYZ
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity at human TLR8 stably expressed in human HEK-Blue hTLR8 cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity at R848 stimulated TRL8 overexpressed in HEK293 cells measured after 20 to 24 hrs by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity at human TLR8More data for this Ligand-Target Pair
Affinity DataKd: 21nMAssay Description:Antagonist activity at human TLR8 by Isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 21nMAssay Description:Binding affinity to human TLR8 expressed in HEK-Blue hTLR8 cellsMore data for this Ligand-Target Pair

3D Structure (crystal)