Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 5XVG
TargetSerine/threonine-protein kinase PAK 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50251098(CHEMBL4097816)
Affinity DataIC50: 9nMAssay Description:Inhibition of human PAK4 assessed as enzymatic activity incubated for 20 mins by filter binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PAK 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50251098(CHEMBL4097816)
Affinity DataIC50: 11nMAssay Description:Inhibition of GST-tagged human PAK4 (295 to 591 residues) expressed in Baculovirus expression system by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PAK 5(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50251098(CHEMBL4097816)
Affinity DataIC50: 15nMAssay Description:Inhibition of full length recombinant human His-tagged PAK5 (295 to 591 residues) expressed in Baculovirus expression system by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PAK 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50251098(CHEMBL4097816)
Affinity DataKi:  9nMAssay Description:Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)