Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 5Y2F
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Shanghai Jiao-Tong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50528216(CHEMBL4440358)
Affinity DataEC50:  5.70E+3nMAssay Description:Inhibition of SIRT6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Shanghai Jiao-Tong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50528216(CHEMBL4440358)
Affinity DataEC50:  1.00E+4nMAssay Description:Activation of wild type full length human SIRT6 expressed in Escherichia coli BL21(DE3) using RHKK-ac-AMC as substrate incubated for 2 hrs in presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Shanghai Jiao-Tong University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50528216(CHEMBL4440358)
Affinity DataEC50:  5.70E+3nMAssay Description:Activation of wild type human N-terminal full length SIRT6 deacetylation (8 to 533 residues) expressed in Escherichia coli BL21 (DE3) expression syst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)