Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 5YLV
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50008977((8-Benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-yl)-...)
Affinity DataIC50: 65nMAssay Description:Inhibition of H+/K+ ATPase as reduced acid formation in rabbit gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPotassium-transporting ATPase alpha chain 1(Pig)
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM50008977((8-Benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-yl)-...)
Affinity DataIC50: 101nMAssay Description:Binding affinity of compound towards H+/K+ ATPase for activation was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50008977((8-Benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-yl)-...)
Affinity DataIC50: 1.59E+3nMpH: 7.4Assay Description:Inhibition of purified H+/K+ ATPase at pH 7.4 as released inorganic phosphate from ATP using hog stomach gastric membrane vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)