Report error Found 4 Enz. Inhib. hit(s) for PDB: 5YVE
Affinity DataIC50: 45nMAssay Description:Antagonist activity at human recombinant P2X3 receptor expressed in HEK293-Tet-on cells assessed as alpha,beta-methylene-ATP-stimulated Ca2+ influx b...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 45nMAssay Description:Antagonist activity at human recombinant P2X3 receptor expressed in HEK293-Tet-on cells assessed as alpha,beta-methylene-ATP-stimulated Ca2+ influx b...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Antagonist activity at human P2X3R expressed in HEK293 cells assessed as reduction in alphabeta-MeATP-induced intracellular Ca2+ influx pretreated wi...More data for this Ligand-Target Pair
Affinity DataIC50: 52.2nMAssay Description:The antagonist property of the compounds disclosed herein was determined using the FLIPR (fluorescence imaging plate reader) method, showing that the...More data for this Ligand-Target Pair