Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 6ALB
LigandPNGBDBM50453950(CHEMBL4203082 | US11247989, Example 88)
Affinity DataEC50:  32nMAssay Description:Inhibition of P300/CBP in human MV4-11 cells assessed as downregulation of MYC expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCREB-binding protein(Human)
Genentech

US Patent
LigandPNGBDBM50453950(CHEMBL4203082 | US11247989, Example 88)
Affinity DataIC50: 1.16nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetCREB-binding protein(Human)
Genentech

US Patent
LigandPNGBDBM50453950(CHEMBL4203082 | US11247989, Example 88)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant His-tagged CBP (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)