Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) for PDB: 6AUM
TargetBifunctional epoxide hydrolase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM158481(US9029401, 1728 (t-TUCB))
Affinity DataIC50: 0.280nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using PHOME as substrate assessed as 6-methoxynaphthaldehyde product formation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBifunctional epoxide hydrolase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM158481(US9029401, 1728 (t-TUCB))
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant sEHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBifunctional epoxide hydrolase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM158481(US9029401, 1728 (t-TUCB))
Affinity DataIC50: 0.400nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional epoxide hydrolase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM158481(US9029401, 1728 (t-TUCB))
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in baculovirus-infected High Five cells S9 fraction using CMNPC substrate by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional epoxide hydrolase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM158481(US9029401, 1728 (t-TUCB))
Affinity DataIC50: 0.900nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2015
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetBifunctional epoxide hydrolase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM158481(US9029401, 1728 (t-TUCB))
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using CMNPC as fluorescent substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional epoxide hydrolase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM158481(US9029401, 1728 (t-TUCB))
Affinity DataIC50: 1nMAssay Description:Inhibition of human soluble epoxide hydrolase using CMNPC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional epoxide hydrolase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM158481(US9029401, 1728 (t-TUCB))
Affinity DataKi:  156nMAssay Description:Competitive inhibition of human recombinant soluble epoxide hydrolase expressed in baculovirus-infected High Five cells S9 fraction using varying CMN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)