Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) for PDB: 6AVT
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50370655(CHEMBL485652)
Affinity DataKd:  6.05E+5nMAssay Description:Inhibition of DNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase M184V mutant assessed as incorporation of d4TMP by burst assay usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50370655(CHEMBL485652)
Affinity DataKd:  2.32E+5nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase M184V mutant assessed as incorporation of d4TMP by burst assay usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Biota

Curated by ChEMBL
LigandPNGBDBM50370655(CHEMBL485652)
Affinity DataKi:  56nMAssay Description:Inhibitory constant against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50370655(CHEMBL485652)
Affinity DataKi:  370nMAssay Description:Inhibition of HIV1 Reverse transcriptase P119S/T165A mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50370655(CHEMBL485652)
Affinity DataKi:  480nMAssay Description:Inhibition of HIV1 Reverse transcriptase P119S/M184V mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50370655(CHEMBL485652)
Affinity DataKi:  640nMAssay Description:Inhibition of HIV1 Reverse transcriptase P119S mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50370655(CHEMBL485652)
Affinity DataKi:  790nMAssay Description:Inhibition of HIV1 Reverse transcriptase M184V mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50370655(CHEMBL485652)
Affinity DataKi:  1.05E+3nMAssay Description:Inhibition of HIV1 Reverse transcriptase P119S/T165A/M184V mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)