Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 6CEP
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM23222(carbamoylformic acid | Oxalamic acid | Oxamidic Ac...)
Affinity DataIC50: 3.38E+4nMAssay Description:Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in insect cells using pyruvate as substrate after 10 mins by UV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM23222(carbamoylformic acid | Oxalamic acid | Oxamidic Ac...)
Affinity DataIC50: 3.38E+4nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetL-lactate dehydrogenase B chain(Mouse)
Instituto Politécnico Nacional

LigandPNGBDBM23222(carbamoylformic acid | Oxalamic acid | Oxamidic Ac...)
Affinity DataIC50: 6.00E+4nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM23222(carbamoylformic acid | Oxalamic acid | Oxamidic Ac...)
Affinity DataKi:  9.44E+4nMAssay Description:Competitive inhibition of human LDH1 in presence of NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetL-lactate dehydrogenase B chain(Bovine)
University of Mississippi

LigandPNGBDBM23222(carbamoylformic acid | Oxalamic acid | Oxamidic Ac...)
Affinity DataIC50: 1.23E+5nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)