Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 6F23
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Sprint Bioscience

Curated by ChEMBL
LigandPNGBDBM50255615(CHEMBL4061204)
Affinity DataIC50: 5nMAssay Description:Binding affinity to recombinant human full length N-terminal His tagged-MTH1 expressed in Escherichia coli at 3 mM by isothermal titration calorimetr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Sprint Bioscience

Curated by ChEMBL
LigandPNGBDBM50255615(CHEMBL4061204)
Affinity DataEC50:  63nMAssay Description:Binding affinity to MTH1 in human K562 cells assessed as concentration required to achieve half of the maximal stabilization of protein at 54 degC af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)