Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 6HKN
TargetMitogen-activated protein kinase 7(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50507990(CHEMBL4469661)
Affinity DataIC50: 51nMAssay Description:Inhibition of His-tagged MAP2K5 activated N-terminal GST-tagged recombinant human ERK5 (1 to 398 residues) expressed in Escherichia coli using biotin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 7(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50507990(CHEMBL4469661)
Affinity DataIC50: 160nMAssay Description:Inhibition of ERK5 in human SN12C cells transduced with MEF2-responsive transcription element assessed as reduction in MEF2 transcription by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)