Report error Found 4 Enz. Inhib. hit(s) for PDB: 6HMM
Affinity DataKd: 1.5nMAssay Description:Binding affinity to human PARG assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 3.00E+4nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+4nMpH: 7.4Assay Description:Briefly, PARG in vitro assays were conducted in a total volume of 15 μL in a standard 384-well format. A total of 5 μL of human full length...More data for this Ligand-Target Pair
Affinity DataEC50: 8.10E+4nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair