Report error Found 2 Enz. Inhib. hit(s) for PDB: 6K1S
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics
Curated by ChEMBL
Prelude Therapeutics
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant PRMT5/MEP50 expressed in baculovirus infected High-five cells using histone 4 peptide as substrate in presence of [3H...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 22nMAssay Description:Inhibition of PRMT5 in human Granta-519 assessed as reduction in sDMA production incubated for 3 days by Western blotting analysisMore data for this Ligand-Target Pair