Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 6LVY
TargetToll-like receptor 7(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50189516(9-benzyl-2-(2-methoxyethoxy)-8-oxoadenine | SM-360...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at TLR7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50189516(9-benzyl-2-(2-methoxyethoxy)-8-oxoadenine | SM-360...)
Affinity DataEC50:  399nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells coexpressing pNiFty2-SEAP reporter by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50189516(9-benzyl-2-(2-methoxyethoxy)-8-oxoadenine | SM-360...)
Affinity DataEC50:  944nMAssay Description:Agonist activity at TLR7 in human PBMC assessed as induction of IN-12 stimulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 7(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50189516(9-benzyl-2-(2-methoxyethoxy)-8-oxoadenine | SM-360...)
Affinity DataEC50:  1.17E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells assessed as induction of NFKappaB activity after 24 hrs by SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)