Report error Found 4 Enz. Inhib. hit(s) for PDB: 6NAD
Affinity DataKd: 0.470nMAssay Description:ThermoFluor is a fluorescence based assay that estimates ligand binding affinities by measuring the effect of a ligand on protein thermal stability (...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKd: 0.5nMAssay Description:Displacement of thermofluor from human recombinant N-terminal TEV cleavage site-fused-His-tagged RORgammat LBD expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:A reporter assay was used to test functional activity of RORγt modulatory compounds on transcriptional activation driven by the RORγt LBD. ...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inverse agonist activity at GAL4-DNA binding domain-fused human full length RORgammat LBD expressed in pGL4.31 transfected HEK293T cells assessed as ...More data for this Ligand-Target Pair