Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 6NCF
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50241262(3-O-acetyl-11-keto-beta-boswellic acid | 3alpha-ac...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of lipoxygenase 5 product formation from endogenous substrate in Calcium and ionophore-stimulated polymorphonuclear leukocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50241262(3-O-acetyl-11-keto-beta-boswellic acid | 3alpha-ac...)
Affinity DataIC50: 3.56E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in insect cells assessed as decrease in production of 5-HPETE and 5-HETE using arachidonic acid as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50241262(3-O-acetyl-11-keto-beta-boswellic acid | 3alpha-ac...)
Affinity DataIC50: 3.56E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in insect cells assessed as decrease in production of 5-HPETE and 5-HETE using arachidonic acid as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)