Affinity DataEC50: 320nMAssay Description:Agonist activity at RoRc-LBD (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 reporter assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 110nMAssay Description:Inhibition of Gal4-RORgamma-LBD (180 to 507 residues) (unknown origin) expressed in HEK293T cells after 24 hrs by dual-luciferase reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]T0901317 from human RoRc expressed in HepG2 cells by scintillation proximity binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of human GAL4-fused RORgamma transfected in HEK293 cells co-transfected with G6Pase by luciferase reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Antagonist activity at full-length RORgamma (unknown origin) expressed in 293T cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Antagonist activity at Gal4-fused RORgamma (unknown origin) expressed in 293T cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 910nMAssay Description:Displacement of N-terminal biotinylated SRC1-4 coactivator peptide from N-terminal His6-fused human RORgamma-LBD (262 to 507 residues) expressed in E...More data for this Ligand-Target Pair
Affinity DataIC50: 3.54E+3nMAssay Description:Antagonist activity at human His6-tagged RORgamma ligand binding domain (262 to 507 aa) assessed as inhibition of SRC1-4 co-activator peptide recruit...More data for this Ligand-Target Pair
Affinity DataKi: 105nMAssay Description:Binding affinity to RORc (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
