Report error Found 5 Enz. Inhib. hit(s) for PDB: 6TV4
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of human Notum (81 to T451 residues) Cys330Ser mutant using OPTS substrate incubated for 16 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human notum using OTPS as substrate incubated for 16 hrs by fluorescent based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.58E+4nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant in human HEK293 cells expressing Renilla and STF reporter gene and measured after 2...More data for this Ligand-Target Pair
Affinity DataEC50: 4.60E+4nMAssay Description:Inhibition of human notum transfected with HEK293 cell incubated for 16 hrs by luciferase assayMore data for this Ligand-Target Pair
Affinity DataKd: 8.50E+4nMAssay Description:Binding affinity to human Notum (S81 to T451 residues) Cys330Ser mutant expressed in human HEK293T cells by SPR analysisMore data for this Ligand-Target Pair

3D Structure (crystal)