Report error Found 5 Enz. Inhib. hit(s) for PDB: 6UE6
TargetHistone-lysine N-methyltransferase NSD2(Human)
University of Texas Medical Branch (UTMB)
Curated by ChEMBL
University of Texas Medical Branch (UTMB)
Curated by ChEMBL
Affinity DataKd: 349nMAssay Description:Binding affinity to NSD2 PWWP1 domain (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
3D Structure (crystal)TargetHistone-lysine N-methyltransferase NSD2(Human)
University of Texas Medical Branch (UTMB)
Curated by ChEMBL
University of Texas Medical Branch (UTMB)
Curated by ChEMBL
Affinity DataKd: 3.40E+3nMAssay Description:Binding affinity to NSD2 PWWP1 domain (unknown origin) assessed as dissociation constant in presence of 0.5% DMSO by surface plasmon resonance analys...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase NSD2(Human)
University of Texas Medical Branch (UTMB)
Curated by ChEMBL
University of Texas Medical Branch (UTMB)
Curated by ChEMBL
Affinity DataKd: 7.00E+3nMAssay Description:Binding affinity to NSD2 PWWP1 domain (unknown origin) assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase NSD2(Human)
University of Texas Medical Branch (UTMB)
Curated by ChEMBL
University of Texas Medical Branch (UTMB)
Curated by ChEMBL
Affinity DataIC50: 1.73E+4nMAssay Description:Displacement of Halo-tagged Histone H3.3 from Nanoluc-tagged NSD2- PWWP1 (unknown origin) transfected in human U2OS cells preincubated for one day fo...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase NSD2(Human)
University of Texas Medical Branch (UTMB)
Curated by ChEMBL
University of Texas Medical Branch (UTMB)
Curated by ChEMBL
Affinity DataIC50: 2.47E+4nMAssay Description:Binding affinity to N-terminal His6/Sumo-tagged NSD2 PWWP1 domain (211 to 350 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) usi...More data for this Ligand-Target Pair